Primary bone tumours can be classified according to the tissue of differentiation, using the WHO system. Tumours are classified as:
- cartilage tumours (eg osteochondroma, chondrosarcoma)
- osteogenic tumours (eg osteoid osteoma, osteosarcoma)
- fibrogenic tumours (eg desmoplastic fibroma, fibrosarcoma)
- fibrohistiocytic tumours (eg benign fibrous histiocytoma, malignant fibrous histiocytoma)
- Ewing sarcoma/Primitive Neuroectodermal tumour (PNET)
- Haemopoetic tumours (eg plasma cell myeloma)
- Giant cell tumour of bone
- Notochordal tumours (eg chordoma)
- Vascular tumours (eg haemangioma)
- Smooth muscle tumours (eg leiomyosarcoma)
- Lipogenic tumours (eg lipoma, liposarcoma)
- Neural tumours (eg neurilemmoma)
- Miscellaneous tumours (eg adamantinoma)
- Miscellaneous lesions (eg aneurysmal bone cyst)
- Joint lesions (eg synovial chondromatosis)
For more information look here.
A simpler classification can also be helpful:
- Cartilage forming tumours
- Bone forming tumours
- Fibrous tumours
- Non-matrix producing tumours
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